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Novel Skin-Whitening Solution

The next generation skin-whitening ingredient from
Chinese Medicine Dendrobium 

D2 Youth Factor

Enhancing Skin Brightness in 4 Weeks

Renowned Health-Promoting Antioxidant

Inhibiting Melanin Production

No Skin Irritation

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Renowned Health-Promoting Antioxidant

We had demonstrated that the use of D2 Youth Factor from Dendrobium plants significantly reduced the generation of oxidative radicals in inflammatory conditions, such as pancreatitis and pulmonary injury, in vivo. D2 Youth Factor can reduce protein oxidation and lipid peroxidation, and attenuate NADPH oxidase activity and the generation of reactive oxygen species (ROS).

Inhibiting Melanin Production

In addition to the anti-oxidative property, D2 Youth Factor have been suggested for hyperpigmentation therapy as they were found to significantly reduce melanin formation by inhibiting tyrosinase activity and the expression levels of tyrosinase-related proteins (TRP-1 and TRP-2) in melanocytes. Such usage was granted with patents in the US, mainland China, Hong Kong, Taiwan, Japan, Malaysia and Singapore.

Enhancing Skin Brightness in 4 Weeks

A 4-week human skin trial has been done by a third party in Singapore. From the trial results, the skin whiteness has a significant increase in 2 weeks. After 4 weeks, the average skin brightness (ITA° value) from all volunteers has increased by 6.35%. The average skin melanin index (MI index) from the half faces applied with D2 Youth Factor has significantly decreased while the MI index from the half faces applied placebo has increased. This implied that D2 Youth Factor has a promising skin-whitening effect.

No Skin Irritation

In our cellular experiment, D2 Youth Factor showed lower cytotoxicity to the human cell when compare to other commonly used active ingredients. From the feedback of our customers, no irritation has been reported from the usage of the cosmeceutical products containing D2 Youth Factor on the human skin. Hence, our products can be applied on any skin type.

© 2024 by Gihon Research and Development

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